June 24th, 2025
Amphithéâtre Buffon – Université Paris Cité
15 rue Hélène Brion – 75013 Paris
The opening symposium of the Inserm FIBER (For Integrative Boost to Repair) network will be held on Tuesday June 24th, 2025 in the Buffon amphitheatre (Université Paris Cité - Paris 13). The day will be structured around scientific presentations on the various aspects of research on fibrosis that the network wishes to address. A keynote lecture on Omics and AI in fibrosis models will be given by Christoph Kuppe (RWTH Aachen University). The meeting will end with a discussion session during which the network coordinators will present the FIBER network structuring project to exchange ideas and move forward with its implementation.
This symposium is open to the scientific community interested in fibrosis research.
Registration is free but compulsory.
The event will be held on-site only to encourage interaction and structure the Network.
>>>>>>>>>> Program
The organizing committee
Thomas Baumert, Chantal Boulanger, Kristell Dervieux, Nathalie Grivel, Pierre-Louis Tharaux
Program
9:15 Welcome coffee
9:45 - 9:55 Introduction - Chantal Boulanger, director of IT PMN
9:55 - 10:00 Opportunities and roadmap to federate against fibrosis - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network
Session 1 - Fibroblast Heterogeneity and Fibrosis
Chairs: Thomas Baumert and Pierre-Louis Tharaux
10:00 - 10:30 Fibroblast heterogeneity in Cancer and Fibrosis - Fatima Mechta-Grigoriou, Institut Curie, Inserm, PSL Research University, Paris, France
Session 2 - Epithelial drivers of fibrosis
Chairs: Olivia Lenoir and Sophie Lotersztajn
10:30 - 11:00 Claudin-1 as a mediator and therapeutic target for fibrotic diseases - Thomas Baumert, Inserm, University of Strasbourg, France
11:00 - 11:30 Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin (NGAL) - Rachel Marion-Letellier, Inserm, University of Rouen Normandie, France
11:30 - 12:00 Plakins and Lung fibrosis - Bruno Crestani, Inserm, Université Paris Cité, France
12:00 - 13:30 Lunch
Session 3 - Beyond the Multiome
Chairs: Pierre-Louis Tharaux and Thomas Baumert
13:30 - 14:15 Keynote lecture Integrating -Omics and AI in Fibrosis Models- Christoph Kuppe, RWTH Aachen University, Germany
Session 4 - Part 1 Inflammatory Drivers of Fibrosis
Chairs: Capucine Trollet and Christophe Guignabert
14:15 - 14:45 Tissue remodeling versus fibrosis in skeletal muscle regeneration - Bénédicte Chazaud, Inserm, CNRS, Université Claude Bernard Lyon 1, France
14:45 - 15:15 Adipose tissue fibrosis: from clinic to cellular mechanisms - Geneviève Marcelin, Inserm, Sorbonne Université, Paris, France
15:15 - 15:30 Coffee break
Session 4 - Part 2 Inflammatory Drivers of Fibrosis
Chairs: Barbara Garmy-Susini and David Launay
15:30 - 16:00 Inflammation and cardiac fibrosis - Jean-Sébastien Silvestre, Inserm, Université Paris Cité, France
16:00 - 16:30 Vascular Remodeling in Pulmonary Hypertension: Role of the TGF-ß Family of Ligands - Christophe Guignabert, Inserm, Université Paris-Saclay, France
16:30 - 16:45 European Calls - Cluster Health - Aude Raimbault, Inserm European Affairs Officer
16:45 - 17:30 Discussion & networking, discussions for webinars and future seminars.
17:30 - 17:45 Conclusion - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network