June 24th, 2025
Amphithéâtre Buffon – Université Paris Cité
15 rue Hélène Brion – 75013 Paris
The opening symposium of the Inserm FIBER (For Integrative Boost to Repair) network was held on Tuesday June 24th, 2025 in the Buffon amphitheatre (Université Paris Cité - Paris 13). The day was structured around scientific presentations on the various aspects of research on fibrosis that the network wishes to address. Christoph Kuppe (RWTH Aachen University) gave a keynote lecture on Omics and AI in fibrosis models. The meeting ended with a discussion session during which the network coordinators presented the FIBER network structuring project to exchange ideas and move forward with its implementation.
>>>>>>>>>> Program
The organizing committee
Thomas Baumert, Chantal Boulanger, Kristell Dervieux, Nathalie Grivel, Pierre-Louis Tharaux
Program
9:15 Welcome coffee
9:45 - 9:55 Introduction - Chantal Boulanger, director of IT PMN
9:55 - 10:00 Opportunities and roadmap to federate against fibrosis - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network
Session 1 - Fibroblast Heterogeneity and Fibrosis
Chairs: Thomas Baumert and Pierre-Louis Tharaux
10:00 - 10:30 Fibroblast heterogeneity in Cancer and Fibrosis - Fatima Mechta-Grigoriou, Institut Curie, Inserm, PSL Research University, Paris, France
Session 2 - Epithelial drivers of fibrosis
Chairs: Olivia Lenoir and Sophie Lotersztajn
10:30 - 11:00 Claudin-1 as a mediator and therapeutic target for fibrotic diseases - Thomas Baumert, Inserm, University of Strasbourg, France
11:00 - 11:30 Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin (NGAL) - Rachel Marion-Letellier, Inserm, University of Rouen Normandie, France
11:30 - 12:00 Plakins and Lung fibrosis - Bruno Crestani, Inserm, Université Paris Cité, France
12:00 - 13:30 Lunch
Session 3 - Beyond the Multiome
Chairs: Pierre-Louis Tharaux and Thomas Baumert
13:30 - 14:15 Keynote lecture Integrating -Omics and AI in Fibrosis Models- Christoph Kuppe, RWTH Aachen University, Germany
Session 4 - Part 1 Inflammatory Drivers of Fibrosis
Chairs: Capucine Trollet and Christophe Guignabert
14:15 - 14:45 Tissue remodeling versus fibrosis in skeletal muscle regeneration - Bénédicte Chazaud, Inserm, CNRS, Université Claude Bernard Lyon 1, France
14:45 - 15:15 Adipose tissue fibrosis: from clinic to cellular mechanisms - Geneviève Marcelin, Inserm, Sorbonne Université, Paris, France
15:15 - 15:30 Coffee break
Session 4 - Part 2 Inflammatory Drivers of Fibrosis
Chairs: Barbara Garmy-Susini and David Launay
15:30 - 16:00 Inflammation and cardiac fibrosis - Jean-Sébastien Silvestre, Inserm, Université Paris Cité, France
16:00 - 16:30 Vascular Remodeling in Pulmonary Hypertension: Role of the TGF-ß Family of Ligands - Christophe Guignabert, Inserm, Université Paris-Saclay, France
16:30 - 16:45 European Calls - Cluster Health - Aude Raimbault, Inserm European Affairs Officer
16:45 - 17:30 Discussion & networking, discussions for webinars and future seminars.
17:30 - 17:45 Conclusion - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network