République Française Inserm
Institut thématique Immunologie, inflammation, infectiologie et microbiologie

Opening symposium FIBER - June 24th, 2025

June 24th, 2025
Amphithéâtre Buffon – Université Paris Cité
15 rue Hélène Brion – 75013 Paris

The opening symposium of the Inserm FIBER (For Integrative Boost to Repair) network will be held on Tuesday June 24th, 2025 in the Buffon amphitheatre (Université Paris Cité - Paris 13). The day will be structured around scientific presentations on the various aspects of research on fibrosis that the network wishes to address. A keynote lecture on Omics and AI in fibrosis models will be given by Christoph Kuppe (RWTH Aachen University). The meeting will end with a discussion session during which the network coordinators will present the FIBER network structuring project to exchange ideas and move forward with its implementation.

This symposium is open to the scientific community interested in fibrosis research.
Registration is free but compulsory.

The event will be held on-site only to encourage interaction and structure the Network.


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The organizing committee
Thomas Baumert, Chantal Boulanger, Kristell Dervieux, Nathalie Grivel, Pierre-Louis Tharaux


Program

9:15 Welcome coffee

9:45 - 9:55  Introduction

9:55 - 10:00 Opportunities and roadmap to federate against fibrosis  - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network

Session 1 - Fibroblast Heterogeneity and Fibrosis

10:00 - 10:30 Fibroblast heterogeneity in Cancer and Fibrosis - Fatima Mechta-Grigoriou, Institut Curie, Inserm, PSL Research University, Paris, France

Session 2 - Epithelial drivers of fibrosis

10:30 - 11:00 Claudin-1 as a mediator and therapeutic target for fibrotic diseases - Thomas Baumert, Inserm, University of Strasbourg, France

11:00 - 11:30 Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin (NGAL) - Rachel-Marion Letellier, Inserm, University of Rouen Normandie, France

11:30 - 12:00 Plakins and Lung fibrosis - Bruno Crestani, Inserm, Université Paris Cité, France

12:00 - 13:30 Lunch


Session 3 - Beyond the Multiome

13:30 - 14:15 Keynote lecture Integrating -Omics and AI in Fibrosis Models- Christoph Kuppe, RWTH Aachen University, Germany

Session 4 - Inflammatory Drivers of Fibrosis

14:15 - 14:45 Tissue remodeling versus fibrosis in skeletal muscle regeneration - Bénédicte Chazaud, Inserm, CNRS, Université Claude Bernard Lyon 1, France

14:45 - 15:15 Adipose tissue fibrosis: from clinic to cellular mechanisms - Geneviève Marcelin, Inserm, Sorbonne Université, Paris, France

15:15 - 15:30 Coffee break

15:30 - 16:00 Inflammation and cardiac fibrosis - Jean-Sébastien Silvestre, Inserm, Université Paris Cité, France

16:00 - 16:30 Vascular Remodeling in Pulmonary Hypertension: Role of the TGF-ß Family of Ligands - Christophe Guignabert, Inserm, Université Paris-Saclay, France

16:30 - 17:15 Discussion & networking, discussions for webinars and future seminars.

17:15 - 17:30 Conclusion - Pierre-Louis Tharaux and Thomas Baumert, coordinators of the FIBER network