République Française Inserm
Institut thématique Immunologie, inflammation, infectiologie et microbiologie


French-German Symposium:
The lung at the crossroad of health and disease

April 7th, 2017
Biopark Auditorium - Paris



In partnership with the German Center for Lung Research (DZL), the Physiopathology Metabolism Nutrition ITMO organised a French-German Symposium: the lung at the crossroad of health and disease.

The French German symposium discussed novel concepts and trends in the understanding of the respiratory system in health and disease. It brought together young and senior scientists from France and Germany, giving them the opportunity to discuss, explore the synergies and complementarities of scientific expertise, and foster bilateral scientific collaboration.

French-German Symposium:
The lung at the crossroad of health and disease


Opening ceremony: Christian Boitard (Director ITMO Pathophysiology, Metabolism, Nutrition)  


Session 1: Bronchial and pulmonary remodeling 

    Chair : Marina Pretolani (UMR 1152 Inserm, Paris), Anne Tsicopoulos (UMR 1019 Inserm, Lille) & Pascal Chanez (UMR 1067 Inserm, 7333 CNRS, Marseille)

Reactivation of Developmental Transcription Factors in Idiopathic Pulmonary Fibrosis - Arnaud Mailleux (UMR 1152 Inserm, Paris)


Pulmonary fibrosis and Heat shock protein - Philippe Bonniaud (UMR 1231 Inserm, Dijon)


Bronchial epithelium: a key player in severe asthma - Delphine Gras (UMR 1067 Inserm, 7333 CNRS, Marseille)

11:10-11:40   Role of epithelium-smooth muscle interaction in asthma - Thomas Trian (UMR 1045 Inserm, Bordeaux)

Regulation of proteostasis in chronic lung disease - Silke Meiners (Institute of Lung Biology and Disease, Comprehensive Pneumology Center, Munich)


Origin and fate of the mesenchymal cells in the lung during development and disease - Saverio Bellusci (German Center for Lung Research, Universities of Giessen and Marburg Lung Center, Giessen)




Session 2: Pulmonary Circulation

    Chair : Christelle Guibert (UMR 1045 Inserm, Bordeaux) & Christophe Guignabert (UMR 999 Inserm, Paris)

KCNK3 dysfunction contributes to the development of pulmonary arterial hypertension - Fabrice Antigny (UMR 999 Inserm, Paris)


mTOR Pathway Activation Drives Lung-Cell Senescence and Emphysema in Chronic Obstructive Pulmonary Disease - Amal Houssaini (UMR 955 Inserm, Créteil & Comprehensive Pneumology Center, Munich)


Matrix remodeling forces pulmonary hypertension: A very stiff story! - Thomas Bertero (UMR 7284 CNRS - UMR 1081 Inserm, Nice)


Epigenetic mechanisms in pulmonary hypertension: A Global perspective - Soni Pullamsetti (Max-Planck Institute for Heart and Lung Research, Bad Nauheim)




Session 3 : Infection – Cystic fibrosis – Environment

    Chair: Mustapha Si-Tahar (UMR 1100 Inserm, Tours)  & Valérie Siroux (UMR 1209 Inserm, Grenoble)

Novel regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) chloride channel - Arnaud Billet (ERL 7368 CNRS, Poitiers)


Genomic mechanisms controlling the differentiation of a mucociliary epithelium - Pascal Barbry (UMR 7275 CNRS, Nice)


Chronic obstructive pulmonary diseases: the influence of diet - Raphaelle Varraso (UMR 1168 Inserm, Villejuif)


Environmental and mucosal microbiota and their role in childhood asthma - Erika Von Mutius (German Center for Lung Research, Comprehensive Pneumology Center, Munich)


Conclusion: Marc Humbert (UMR 999 Inserm, Paris) & Roger Marthan (UMR 1045 Inserm, Bordeaux)